Do Your Own Pest Control recommends D-Fense SC as an effective ladybug killer. The pesticide has very little odor and takes a while to break down when used outside on wall surfaces, so it lasts long to keep ladybugs out of the home.
Cyper WP is another product that gets rid of ladybugs. However, the product leaves residue when sprayed on surfaces that are especially dark. Cyper WP is best used around doors, windows, attic vents and eaves, which are places where ladybugs can easily enter the home. Another product for ridding the home of ladybugs is D-Fense dust, which is weather resistant and can be spread around electrical outlets and pipes.