Experts from the North Carolina State University Cooperative Extension and the Texas A&M Agrilife Extension suggest using baits and mound elimination to control and eliminate fire ants. These basic approaches are effective in treating fully infested areas.
Users apply the bait insecticide throughout the yard or near specific mounds during the warm season, ideally from late August to mid-October. Baits target fire ants foraging near the mound and cause the colony to die out naturally. The individual mound elimination method uses insecticides that are directly applied over the mound. It is the fastest method to kill ants inside a mound, but it may not seep through enough to kill the queen fire ant. In order to control the fire ants throughout the year, experts suggest users follow a two-step method by using the bait first and then following it up with the individual mount treatment after a few days.