The main difference between jute and sisal is that sisal is tougher than jute. Jute and sisal are natural fibers commonly used to make rugs; jute is a strong fiber that is used to make cordage, burlap and gunny, and it is derived from two species of plants in East India. Sisal is the tougher of the two, and it is used to make cordage, twine and hemp.
Jute fibers are soft and resemble wool. When made into a rug, it holds up well in low-traffic areas of the home.
Sisal is an extremely tough natural fiber that can withstand high-traffic use. The fiber is used both in the home such as for rugs, as well as for commercial use. Due to its toughness, it is not soft and can be painful when walked on with bare feet.