Although acrylic paint is considered non-toxic, some acrylic paints may contain toxic pigments. These paints may contain ammonia, which is irritating to sensitive individuals. However, poisoning is unlikely.
According to Princeton University, individuals with ammonia sensitivities may experience eye, nose and throat irritation if they are exposed to acrylic paints with high enough ammonia levels. Individuals who are already sensitized to formaldehyde and are allergic to it may react to the trace amounts found in some acrylic paints.
Although minimal skin contact with acrylic paint is not harmful, safety for skin-safe paints, such as face paints, is determined using standards that measure the safety of cosmetic products meant for skin application. Acrylic paints are not evaluated using those standards.