Tips for playing “The Impossible Quiz” include saving all the skips until the end of the game and watching out for bombs. If there is a bomb on a question, the player has one to 11 seconds to answer correctly. If he doesn't, he gets an immediate game over.
There are 110 questions that players must answer to beat "The Impossible Quiz," ranging from logical problems to mini games. Along the way, players earn skips that allow them to skip questions; there are seven in total. While it's tempting to use these skips to pass difficult problems, players must save the skips until the last question. Without all seven skips, it's impossible to beat the game.
Players also need to be careful not to hit the Tab key on the keyboard during gameplay. Because the Tab key highlights clickable objects, making some of the trick questions in “The Impossible Quiz” easy, pressing it at any point results in an automatic game over.
The developer of “The Impossible Quiz,” Splapp-Me-Do, released a sequel to the game called “The Impossible Quiz 2.” The sequel offers improved presentation and visuals. As of 2015, mobile versions of both games are available for iOS devices.