Issues with a game disc and problems with an Xbox optical drive or other internal hardware commonly cause disc read errors. Disc read errors frequently occur when the game disc is dirty or scratched. Disc read errors can also occur when the Xbox console and game disc are manufactured for different regions.
If the disc is dirty, remove it from the console and clean it before replacing. Scratched game discs that cause disc read errors are generally not repairable.
Hardware issues that cause disc read errors include overheating, optical drive failure and problems with the disc drive tray. An Xbox may be unable to read a disc when it becomes overheated. Blocked ventilation holes or buildup of dust inside the vent holes are the most likely reasons for overheating. Make sure there is nothing blocking the machine's ventilation system. If dust buildup is causing the blockage, remove it with a can of pressurized air.
Failure of the motor inside the optical drive causes disc read errors. When the motor fails, the disc cannot spin, and the machine cannot read it. Failure of the laser inside the optical drive also renders the machine incapable of reading the disc. In both of these cases, replacement of the optical drive is necessary.