There is no limit to what can be spelled with the letters in a Scrabble game. Laying out all the letters opens nearly limitless combinations to create just about any word in the English language.
A list of the highest possible scoring words can be found at MentalFloss.com. Within the game of Scrabble, it can be more difficult to play the wide variety of words the letters can create. Being restricted by the letters drawn and those in play limits combinations. Sites such as WordFind.com and WordSolver.net help turn collections of letters into playable words for Scrabble and other word games.