During World War I, a total of 116,516 American soldiers were killed. That is the seventh most deaths of any country that participated in the war. The United States sent 4,355,000 soldiers to participate in the war, and roughly seven percent of them were either killed, injured or captured.
In terms of total casualties, World War I is the third deadliest war in U.S. history, as of 2014. Only World War II and the American Civil War have caused more American casualties than World War I. Of the total death total during World War I, roughly 10,000 more American deaths were caused by accident or disease than by combat.