While Raphael Sanzio is remembered alongside Leonardo da Vinci and Michelangelo for his artwork, he died significantly younger than either of the other two greats, at age 37. In his early paintings, he imitated his painting master Perugino so closely that early art historians have difficulty distinguishing between the two.
When Raphael was 17, he was declared a master in his own right. He traveled to Florence and began to paint his famed portraits of the Madonna there. He was heavily influenced by Leonardo in his dynamic poses, though his commercial work retained its characteristic tranquility. When he moved to Rome, Michelangelo disliked him immensely, claiming that Raphael was conspiring against him. Despite this, Raphael's work later demonstrated the influence from Michelangelo's painting of the Sistine Chapel, using Michelangelo as an inspiration for the portrait of Heraclitus in his painting "The School of Athens."
Raphael eventually led the arguably largest workshop of students, teaching over 50 pupils and assistants. His students included other masters who came to learn. Raphael was known for his efficient and harmonious teaching style in sharp contrast to Michelangelo, who frequently clashed with his own pupils.
When Raphael died, his death was rumored to have been caused by a night of debauchery with his lover, after which he fell into a fever of 15 days before perishing.