A coastal tribe in southwest Florida, the Calusa Indians primarily lived on foods that they could get from the water. They caught catfish, eels, oysters, lobsters, and other aquatic life.
It is estimated that at their peak, the Calusa Indian population was as much as 50,000. They were not a friendly group, which led them to enter many battles with other Native Americans and explorers. Because they were so knowledgeable about water, they often used it to their advantage when battling with other groups. They would sail up and down the waters in Florida, including the Calooshahatchee River. However, in the early 1700s, they were largely eradicated from Florida. Those who survived the conflicts and diseases brought by explorers moved to Cuba.