Doctors request testing for estradiol (E2) and/or estrone (E1) when a man shows signs of feminization, such as an increase in breast growth. Estrogen testing measures estrogen levels in the body, according to Lab Tests Online.
Estrogen tests measure three different components, each with its own use: estrone (E1), estradiol (E2) and estriol (E3), according to Lab Tests Online. Doctors may order estrogen tests for males to determine the cause of delayed puberty or enlarged breasts, known as gynecomastia. Estrogen tests in men can also help identify a testosterone or androgen deficiency, which causes a relative estrogen excess, and they are sometimes used to diagnose estrogen-producing tumors.
Doctors use estrogen test results to study the increase and decrease of estrogen levels, according to Lab Tests Online. In men, gynecomastia, tumors in the testicles or adrenal glands and delayed puberty are conditions potentially brought about by an increase of estrogen levels. In both men and women, increased levels of estradiol (E2) or estrone (E1) are seen in diagnoses of hyperthyroidism and cirrhosis. Illnesses such as high blood pressure, anemia, and impaired liver and kidney function also affect estrogen levels.
Blood, urine or saliva may be tested to measure estrogen levels, according to Lab Tests Online.