What Are the Withdrawal Symptoms of the Effexor Antidepressant?


Quick Answer

Withdrawal symptoms of Effexor may include sudden irritability, severe dizziness, vomiting, nightmares, and the recurrence of depression symptoms, notes the National Alliance on Mental Illness. Another unique symptom of Effexor withdrawal is the sensation of electrical discharge taking place directly in the patient's brain, often called brain zaps, according to Mental Health Daily.

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Withdrawal symptoms resulting from the cessation of Effexor typically peak around the third day of the withdrawal process, notes Mental Health Daily. Additional side effects that patients can expect include crying spells, fatigue, insomnia, loss of appetite, mood swings and panic attacks.

Brain zaps are a common sensation among patients withdrawing from powerful antidepressant drugs that have short half lives, notes Mental Health Daily. Another symptom common to those who suddenly stop taking Effexor is anger, often accompanied by anxiety. Effexor remains active in the body for slightly more than a single day, and its metabolite leaves the body after two and a half days. Withdrawal symptoms typically occur both upon complete cessation of the drug and on gradual tapering. Withdrawal tends to increase in severity and difficulty depending on the dosage of the drug, the time span in which the drug was taken, and the individual physiology of the patient.

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