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What is Wegner's granulomatosis?

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Wegner's granulomatosis is a condition in which there is inflammation of the veins and arteries of the nasal passages, lungs and kidneys, according to MedlinePlus. Because these blood vessels supply blood to these organs, the inflammation can cause damage due to restricted blood flow. This condition is also referred to as granulomatosis with polyangiitis.

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When there is blood vessel inflammation, it is called vasculitis, reports the Cleveland Clinic. Aside from blood flow restriction, the inflammation can lead to a rupture in a blood vessel of these organs.

Although the direct cause for this rare disorder is not entirely known, it seems to be linked to a problem of the immune system, relates Mayo Clinic. The condition seems to be more prevalent in middle age people, but it can develop in anyone.

Some symptoms of this disorder are infections of the ears or sinuses, fever, feeling tired, weight loss, skin rashes and ocular problems. The condition can be diagnosed with different tests like biopsies of different organs, blood test, a chest X-ray and a urine test to detect signs of kidney problems. Once a diagnosis is made, different strong medications may be prescribed. Some medications are for the suppression of the immune system. Other medications used may be corticosteroids, reports the Cleveland Clinic. Wegner's granulomatosis is a serious condition that requires treatment. Without it, the disease can be fatal.

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