To reduce the risk of complications when taking alendronate sodium, avoid taking other vitamins, calcium supplements or antacids for at least half an hour after taking alendronate sodium, according to RxList. Also, avoid laying down for the same period of time, and consult with a physician if taking other drugs.
When prescribed alendronate sodium tablets once per day, avoid compensating for missed doses by double-dosing later on in the day, warns RxList. Additionally, any individual who has difficulty swallowing, a vitamin D deficiency, dental problems or kidney disease should consult with a doctor before taking alendronate sodium. Alendronate sodium may be detrimental to individuals with ulcers or other problems in the esophagus or stomach. Individuals who are allergic to alendronate or who suffer from low levels of calcium in the blood, a condition called hypocalcemia, should avoid taking alendronate. Patients taking alendronate sodium should avoid food and beverages, except water, for 30 minutes after taking the drug.
Aspirins and non-steroidal anti-inflammatory drugs can interact with alendronate sodium, notes RxList. Avoid taking celecoxib, commonly known as Celebrex, when undergoing alendronate sodium treatment. Diclofenac, commonly known as Arthrotec, Voltaren, Flector Patch, Cambia or Cataflam, may also provoke undesired secondary reactions. Ibuprofen, typically sold as Motrin or Advil, can react with alendronate sodium.