What Is the Best Way to Stop a Toothache in the Middle of the Night?

Taking a nonprescription pain reliever such as ibuprofen or acetaminophen is the best way to help relieve the pain of a toothache, according to eMedicineHealth. Using oil of clove on the affected tooth may also help numb the pain.

Oil of clove is available at most pharmacies, notes HowStuffWorks. It should be applied directly to the affected tooth in order to numb the nerve. Oil of clove should not be applied to the gums, as it causes burning. Follow the directions on the package, taking care not to use too much at a time in order to prevent overdose.

Rinsing the mouth with warm water, and sleeping with the head of the bed elevated can also ease toothache pain, states About.com. Keeping the head elevated can reduce the discomfort caused by swelling and pressure. Warm salt water removes debris and is an effective antiseptic. One teaspoon of salt per glass of water is a suggested ratio, advises HowStuffWorks.

Cold compresses or ice packs may be used to reduce any swelling, according to HowStuffWorks. Placing a thin cloth barrier between the compress or cold pack will minimize skin damage due to cold. Ice should be applied for no more than 20 minutes at a time, explains Healthline.com. Let the skin come back to normal temperature between icing sessions.