The Virginia creeper plant, also called American ivy, ampelopsis and woodbine, can cause a skin rash, according to the Poison Ivy, Oak & Sumac Information Center. The Virginia creeper plant has sap that contains oxalate crystals, a substance known to cause skin irritation and rash.
The Virginia creeper plant grows wild and invasively in some areas but is considered an ornamental plant in others. It is often mistaken for poison ivy because its leaves are also red in the spring before turning green later, according to the Poison Ivy, Oak & Sumac Information Center. Virginia creeper often grows alongside poison ivy as it prefers the same growing conditions.