Venous reflux is a disease in which the valves that control the flow of blood in the veins in the legs do not properly close, allowing for the backwards flow of blood to the legs, according to Sapheon. This condition afflicts more than 30 million people in the United States.
The John C. Lincoln Health Network explains that the most common symptom of venous reflux is swelling of the ankles. Because the veins within the leg are not able to normally pump blood to the heart, gravity pulls blood to the veins in the calf and ankle causing pain, swelling and vein discoloration. Sapheon notes that treatment options vary depending on the severity of the condition and include vein removal surgery, sclerotherapy and laser or radio-frequency treatment.