Does Vegetable Purine Make Uric Acid Level and Gout Worse?

Vegetables that are high in purines do not increase uric acid and make gout worse, according to the Arthritis Foundation. While doctors once told gout patients to avoid vegetables such as mushrooms, asparagus and spinach, a 2012 study indicates no connection between vegetable purine levels and gout.

Though certain vegetables have higher levels of purine than others, their benefits appear to outweigh any negative effects, the Arthritis Foundation explains. Also, by comparison, all vegetables contain lower levels of purines than meats. Once ingested, the body converts purines to uric acid. High levels of uric acid in the blood cause crystals to form. When these lodge in the joints, gout pain and inflammation occur.