Dimethylsulfoxide (DMSO) creams and gels are prescribed in various strengths to ease pain associated with cancer treatment, shingles, nerve pain and osteoarthritis, states WebMD. Hypericum, which is also known as St. John's wort, is often used as a topical treatment for atopic dermatitis and psoriasis, according to Mayo Clinic.
DMSO can be taken orally or applied topically, states WebMD. Gel that contains 25 to 45 percent DMSO is commonly prescribed for osteoarthritis patients. The gel is applied to the painful area three to four times a day. A 50 percent DMSO solution is often prescribed for nerve pain and is applied for up to three weeks. Self-treatment with industrial-grade DMSO is dangerous because the substance contains impurities that can penetrate the skin and cause health problems.
Hypericum is also commonly found in pill and cream forms, according to Mayo Clinic. The oral supplement is used to treat depression, irritable bowel syndrome, menopausal symptoms and seasonal affective disorder. Cream with 1.5 percent hypericum can be used twice daily to treat atopic dermatitis, and hypericum ointment is often used on skin affected by psoriasis. Research has shown that hypericum may improve wound healing and diminish scarring. Petroleum jelly with 20 percent hypericum can be applied to healing wounds daily.