Products sold by Zero Xtreme include weight loss capsules that the U.S. Food and Drug Administration advises consumers not to purchase or consume, as of July 2015, according to the FDA. Zero Xtreme capsules contain desmethylsibutramine and sibutramine, a controlled substance. Citing safety concerns, federal regulators removed sibutramine from the market in October 2010. Congestive heart failure, stroke, arrhythmia and coronary artery disease patients who use the capsules expose themselves to a substantial risk of harm.
In some patients, sibutramine increases pulse rate or blood pressure, and desmethylsibutramine has similar structural properties to sibutramine, explains the FDA. The Zero Xtreme capsules can interact with other patient medications and produce life-threatening situations. Products for weight loss, bodybuilding and sexual enhancement that contain hidden chemicals and drugs are a part of a developing trend. The FDA cautions consumers to be wary of dietary supplements and products advertised as all natural, because it is impossible for the agency to test all such products for hidden ingredients that may pose dangers to consumers.
Sibutramine is no longer available in the United States, and clinical study results show that individuals who take sibutramine increase their risk of strokes and heart attacks, according to MedlinePlus. People use the medication as part of a diet and exercise program for weight reduction. Classified as an appetite suppressant, sibutramine affects the brain's appetite control centers to reduce the desire for food.