Prostaglandin analogs, which are found in eye medications used for glaucoma, can change a patient's eye color. This can be a side effect of using prescribed eye drops with this active ingredient, states the Glaucoma Research Foundation. Some common glaucoma eye drops that contain prostaglandin analogs are available under different generic and brand names.
For example, the brand name Lumigan is also available in the generic form called bimatoprost. Some other glaucoma eye drops with this substance are Travatan and Zioptan, according to WebMD. These eye drops are useful for glaucoma because they can remove excess fluid from the eye to lower its pressure. The medication also can decrease the formation of eye fluids.
Changes in eye color tend to affect more commonly people with hazel or light eye color. The iris is the part of the eye that can become darker. The change in eye color can be irreversible. The medication can also cause color changes to the eyelid area, where it might get darker, reports WebMD.
Patients, who use this medication in one eye only may have two different eye colors. Although this is one side effect of using eye drops containing prostaglandin analogs, there can be other side effects, such as a burning sensation and redness.
Glaucoma is an eye condition where the optic nerve located at the back of the eye can be damaged when there is buildup of fluid that can increase intraocular pressure. Although increased eye pressure may contribute to the development of glaucoma, the condition can occur without this symptom, notes the National Eye Institute.