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What is a Trimix injection?

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Quick Answer

A Trimix injection is a combination of three medications, papaverine, phentolamine and alprostadil, that is used to treat erectile dysfunction, as confirmed by WebMD. The injection works by increasing blood flow to the penis.

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Full Answer

Trimix is injected into the penis before sexual intercourse, relaxing the muscles surrounding the blood vessels in order to increase blood flow, according to WebMD. The erection can last from 30 minutes to more than one hour depending on how much medicine is injected. It successfully produces an erection in approximately 90 percent of men, and it may be prescribed for erectile dysfunction resulting from physical or psychological factors.

The medication must be mixed by a pharmacist, and a doctor often gives the patient an initial injection in the office to ensure it works properly and to test for adverse reactions, as stated by WebMD. Each of the three medications used in Trimix may cause side effects, which may include pain at the site of the shot, bleeding, nausea, dizziness and others. The injection should not be used more frequently than every other day, and excessive injections may lead to scarring of the penis. Up to 60 percent of men stop using injections due to problems such as cost, discomfort and partner relationship issues.

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