Depending on the severity of nerve pain, treatment may include prescription medications, over-the-counter treatments or a combination of the two, notes WebMD. OTC treatments include topical creams and ointments, painkillers, and vitamins. Having a deficiency of vitamin B12 may cause or aggravate nerve pain.
Acetaminophen, aspirin and ibuprofen may help relieve mild nerve pain, states WebMD. Prescription drugs that can effectively treat nerve pain include painkillers and a variety of medications initially used to treat seizures and depression, reports MedicineNet.com. Acupuncture, physical therapy and relaxation methods, such as deep breathing, yoga and meditation, may also help alleviate nerve pain, says WebMD.