As of 2015, the antibiotic vancomycin is frequently the treatment for a staph infection because many strains have become resistant to other medications, according to Mayo Clinic. The best treatment depends on the staph bacteria type causing the infection and which antibiotic works best to stop it.
Staph is an adaptable bacteria, and many strains have become resistant to one or more antibiotics, Mayo Clinic reports. Some of them are called methicillin-resistant Staphylococcus aureus, or MRSA, strains, which can only be treated with vancomycin and other alternative antibiotics that cause more side effects. Other medications routinely used to treat staph infections include sulfa drugs, nafcillin and some types of cephalosporins
It is important for patients to take all of the antibiotics exactly the way they are prescribed, Mayo Clinic stresses. Patients should also ask their doctors for a list of symptoms and signs that may indicate the staph infection is getting worse so that they can receive additional treatment promptly.
Other treatments may also be indicated besides antibiotics, Mayo Clinic states. If staph has infected a wound, the doctor may create an incision in the wound to drain infected fluid. Patients who contract staph around medical devices must have the device removed immediately. This sometimes involves surgery.