What Is the Treatment for Peyronie's Disease?


Quick Answer

Treatments for Peyronie’s disease are designed to alleviate its symptoms and include oral therapy with vitamin E, colchicine and tamoxifen; injection therapy using combinations of sildenafil, vardenafil and tadalafil; iontophoresis; and shockwave therapy, states MedicineNet. In December 2013, collagenase clostridium histolyticum, or Xiaflex, was approved by the Food and Drug Administration for the treatment of Peyronie’s disease. Betamethasone has also been used to decrease penile curvature. Surgery is done when other treatment methods have failed.

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Full Answer

Peyronie’s disease involves the formation of fibrous scar tissue inside the penis. It affects the tunica albuginea, the sheath that surrounds the corpora cavernosa, explains WebMD. The scar tissue is not visible and may cause painful and bent erection. Individuals with Peyronie’s disease may experience pain during sexual intercourse. Peyronie’s disease is diagnosed through a physical exam, which is sometimes done with the penis erect. A biopsy may also be necessary to confirm its diagnosis.

As of August 2015, the cause of Peyronie’s disease remains unknown, according to Mayo Clinic. It is often associated with repeated injury to the penis; although in some men, the disease develops gradually and appears to be unrelated to injury. Certain medical conditions and genetic traits are being investigated on whether they might be connected to the development of the disorder.

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