Treatment options for mucus in the throat include drinking more water and taking guaifenesin to thin the mucus, according to WebMD. Taking antibiotics for a bacterial infection causing postnasal drip reduces throat mucus, and using propped-up pillows at night prevents mucus from collecting in the back of the throat.
Guaifenesin, classified as an expectorant, is available in over-the-counter cough and cold syrups. By thinning the throat mucus, the medication enables an individual to cough it up and expectorate it, which clears the throat, explains MedlinePlus. Loratadine, certirizine and desloratadine are antihistamines that help relieve postnasal drip due to viruses or allergies that lead to excess throat mucus, and they do not induce drowsiness, notes WebMD.