Treatment for itchy skin includes corticosteroid creams, calcineurin inhibitors and oral antihistamines, according to Mayo Clinic. In some cases, it is also appropriate to use antidepressants to ease itchy skin.
Corticosteroid creams are commonly used to treat itchy skin and are available in both over-the-counter and prescription forms, explains Mayo Clinic. These creams are applied directly to the skin and then covered with a wet dressing. Another solution for itchy skin is calcineurin inhibitors. These drugs, such as tacrolimus and pimecrolimus, may be used instead of corticosteroids, especially if the itchy area is small.
A doctor may also recommend an oral antihistamine for those who have itchy skin, according to Mayo Clinic. These medications are available over the counter and include Zyrtec, Claritin and Benadryl. Zyrtec and Claritin are better choices during the day, but Benadryl, which can cause drowsiness, is ideal for those who have itchy skin at night. Some doctors recommend antidepressants, such as Prozac and Zoloft, for some patients to relieve itchy skin. These medications are known as selective serotonin-reuptake inhibitors.
Itchy skin may be caused by underlying conditions, states Mayo Clinic. In these cases, the underlying issue must be treated first. Light therapy, where skin is exposed to various wavelengths of light, may also be used to alleviate itchy skin.