Blood blisters typically heal on their own over time, explains WebMD. Individuals with blood blisters should apply a loose bandage to the affected area. Blood blisters that are painful and large may need to be drained with a needle or straight pin.
When draining a blood blister, patients must sanitize the needle or straight pin with rubbing alcohol and puncture the edge of the blister gently, explains WebMD. The fluid in the blister should be pushed gently to drain out of the puncture hole and flatten the skin. The affected skin must be washed with soap and water, and the remaining skin flap should not be removed. Patients should apply a clean bandage, and apply antibiotic ointment to the skin once the blood blister is drained. Bandages should be changed daily and removed in the evening to let the area of the skin dry.
Blood blisters that are itchy or painful are often soothed with a soak in a cool tub or shower or by applying a cold cloth to the affected skin, according to WebMD. Patients need to watch for signs of infection near the blood blister. Symptoms of an infection include red streaks that extend away from the site of the blister, fever, increased swelling or redness, and pus drainage from the blister. Individuals should consult with a physician if the pain does not subside or if signs of an infection exist.