Medications used in the treatment of alcoholic gastritis include proton pump inhibitors, H2-receptor antagonists and antacids, says Healthline. An example of a proton pump inhibitor is omeprazole. Additionally, drugs such as ranitidine and Pepto-Bismol are used as an H2-receptor antagonist and an antacid respectively.
The production of excess acid in alcoholic gastritis exacerbates the condition. H2-receptor antagonists and proton pump inhibitors relieve alcoholic gastritis by blocking acid production, reducing the amount of secreted acid. Antacids function by neutralizing the secreted hydrochloric acid that is present in the stomach. Other drugs used as proton pump inhibitors include esomeprazole, rabeprazole, lansoprazole and pantoprazole, according to Healthgrades. Nizatidine, cimetidine and famotidine are some of the other H2-receptor antagonists that the Food and Drug Administration has approved.
An H2-receptor antagonist works by binding to the histamine receptors and competitively inhibits the binding and physiological function of histamine. Physiologically, histamine stimulates acid secretion and exacerbates alcoholic gastritis, while the proton pump inhibitors block hydrogen ion secretion by binding to proton pump receptors, reports WebMD. Patients suffering from alcoholic gastritis should completely stop taking alcohol and acidic foods such as citrus because they cause irritation to the lesions present on the gastric wall, thus worsening any ulcers.