Q:

How do you treat epidermolysis bullosa simplex?

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Quick Answer

Epidermolysis bullosa simplex is incurable, and treatment involves managing the blisters and wounds caused by the condition and preventing infection, reports the Genetic and Rare Diseases Information Center. Sometimes surgery may be necessary to correct deformities, graft skin, widen the esophagus or implant a feeding tube, explains Mayo Clinic. Vitamin supplements may help with nutrition deficiencies caused by the inability to eat.

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Full Answer

Epidermolysis bullosa simplex is a genetic disorder that weakens the skin and causes it to easily blister, states the Genetic and Rare Diseases Information Center. Sometimes the inside of the mouth also blisters.

When blisters form on the skin, people need to puncture them in two places with sterile needles so they can drain; otherwise, they can grow larger and spread, according to Mayo Clinic. Soaking the wound in a mild solution of water and salt, bleach or vinegar helps remove bandages and cleans the wound. Patients can cover the wound with petroleum jelly or antibiotic cream and apply a nonstick bandage or gauze. Some adults and older children may need prescription medication to manage pain, and younger children can take nonprescription pain medications.

Blisters on the fingers or toes may cause them to fuse together, and doctors may perform surgery to restore normal motion, notes Mayo Clinic. Blisters within the esophagus may cause it to narrow, and doctors may surgically dilate the esophagus so patients can eat more easily. Skin grafts replace skin damaged by deep wounds.

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