There are a number of canker sore remedies to try at home, including making your own medication, using cayenne pepper or rinsing the mouth, according to HowStuffWorks. Other options include using ice or taking an over-the-counter pain reliever.
One much-touted home remedy for canker sores is a mixture of Milk of Magnesia and Benadryl applied to the sore with a cotton swab, explains HowStuffWorks. A person should not swallow the mixture, as it may numb the throat. Cayenne pepper is also an option for treating a canker sore, because of the capsaicin it contains. Capsaicin, the substance that makes peppers taste hot, helps to desensitize the nerves that cause pain.
Rinsing the mouth with salt, baking soda and hydrogen peroxide can also bring relief to those suffering from the pain of a canker sore, claims HowStuffWorks. Rinsing with aloe vera juice or sage tea may also help. Though ice may not make a canker sore disappear, it certainly helps to make it less painful. Ice can be applied directly to the sore, or a person can drink ice water. An over-the-counter pain reliever, such as ibuprofen or acetaminophen, taken before eating is also a way to ease the pain associated with a canker sore.