Trazadone withdrawal includes symptoms of agitation, anxiety and difficulty sleeping among patients who abruptly stop using the drug. To lessen the risk of such symptoms, doctors advise patients to decrease trazadone dosages slowly, according to MedlinePlus.
Used to treat depression, the prescription medication works by increasing serotonin levels in the brain, explains MedlinePlus. It is available in both standard and extended-release tablets and typically taken with food.
It may take up to two weeks for patients taking trazadone to notice improvements in mood. Common side effects of the drug include headaches, nausea, dry mouth, muscle pain, changes in sexual desire, constipation and diarrhea.