The topical form of the sulfa antibiotic is sulfacetamide sodium and sulfur, according to Drugs.com. The bacteria-fighting medication treats skin conditions such as rosacea, acne, and a flaky, red rash known as seborrheic dermatitis. Patients with kidney disease or sulfa drug allergies should avoid using the antibiotic.
Patients with dry, chapped, irritated or sunburned skin should refrain from using sulfacetamide sodium and sulfur on those areas, notes Drugs.com. Unless their doctors order it, patients should not use the topical antibiotic on areas treated with other medications. Typical side effects include skin inflammation, irritation, itching, stinging or burning. Patients who experience allergic reactions such as facial, tongue or throat swelling; difficulty breathing; or hives should seek emergency medical help immediately.