While some toothpaste products contain the antibacterial ingredient triclosan, the redness and irritation that often result from its application normally outweigh any cosmetic benefits, according to About Health. Because of these side effects, people often experience worsening pimple conditions when using a toothpaste remedy.
The skin on the face is more delicate than skin on other parts of the body, so the ingredients in toothpaste that irritate skin amplify the problem more. Acne spot treatments with benzoyl peroxide, salicylic acid or sulfur are better solutions because they reduce redness and promote faster healing, according to About Health. Many over-the-counter treatments are very inexpensive.