According to NBC News, testosterone supplements do boost men's energy levels, sex drive and mood. However, WebMD points out that these supplements should only be used under a doctor's supervision after low testosterone levels have been verified clinically.
WebMD explains that physician-approved testosterone supplements come in the form of skin patches, mouth patches, topical gels, injections and implants. While oral over-the-counter testosterone supplements are available, these show detrimental side effects affecting the liver. Other negative side effects associated with testosterone supplements of all types include rashes and itching, and testosterone replacement therapy has been shown to worsen several unrelated medical conditions including benign prostatic hypertrophy, sleep apnea and congestive heart failure.