Synvisic-One is a hyaluronan-based synovial fluid replacement injection for people with osteoarthritis, according to Synvisic One's website. The medical term for the procedure is viscosupplementation, according to WebMD.
While some studies have indicated that hyaluronan injections can improve the symptoms of osteoarthritis, a large analysis of medical trials has shown that the benifit of these injections is very small, reports WebMD. The most common reported side effects of hyaluronan, or hyaluronic acid, include mild bruising, heat, redness, swelling or pain at the injection site. Temporary aches and temporary knee inflammation can also occur, and some severe allergic reactions may cause rash, hives, difficulty breathing, tightness in the chest and swelling of cephalic features, reports Drugs.com.