Scar tissue under the skin of the penis, a significant bend of the penis, erection problems, pain and shortening of the penis are symptoms of Peyronie's disease, notes Mayo Clinic. Penis curvature associated with Peyronie's disease may worsen, but it eventually stabilizes in most men, and while the pain associated with the condition normally improves within one to two years, the scar tissue and curvature often persist.
Peyronie's disease is indicated by fibrous scar tissue in the penis that leads to painful, curved erections that can prevent men from having sex or lead to erectile dysfunction, states Mayo Clinic. In a small number of cases, the disease goes away on its own, but in most cases it stabilizes. As of 2015, doctors do not know exactly what causes Peyronie's disease, though they believe it may be related to repeated injuries to the penis from activities such as sex, athletics or accidents.
Heredity, connective tissue disorders, such as Dupuytren's contracture, and age are risk factors associated with Peyronie's disease, according to Mayo Clinic. Men suffering from the disease may also suffer from anxiety and stress associated with being unable to perform sexually. Doctors may ask patients to wait and see how severe their symptoms become or may treat more serious cases of Peyronie's disease with medications or surgery, such as Nesbit plication, incision or excision with grafting or penile implants.