The first symptom of lymphoma is often painless swelling that develops in the neck, groin or under an arm, according to eMedicineHealth. Enlarged lymph nodes sometimes press against a nerve, causing tingling, pain or numbness; a lymphatic vessel, causing leg or arm swelling; or the stomach, causing feelings of fullness. Nonspecific symptoms of lymphoma include fever, weight loss, chills, night sweats and fatigue. Up to 25 percent of lymphoma patients experience itching, often in the lower extremities.
There are two main types of lymphatic cancers or lymphoma: Hodgkin lymphoma and non-Hodgkin lymphoma, explains Mayo Clinic. In Hodgkin lymphoma, cancerous cells in the lymphatic system, which is a part of the immune system, experience abnormal growth and may spread to other areas of the body outside of the lymphatic system. As Hodgkin lymphoma progresses, the ability of the body to fight off infections diminishes. Treatment options include chemotherapy, radiation and stem cell transplant.
Non-Hodgkin lymphoma also attacks the immune system, causing similar symptoms, states MedicineNet. The difference between Hodgkin lymphoma and non-Hodgkin lymphoma is based on the specific type of abnormal cells that develop. Non-Hodgkin lymphoma is significantly more common than Hodgkin lymphoma. As of 2015, it is the fifth most common cancer among women and the sixth most common cancer among men.