General symptoms of leiomyosarcoma include weight loss, tiredness, fever, a mass felt in the body and general malaise, notes the National Organization for Rare Disorders. Other symptoms include nausea and vomiting. Symptoms vary depending on which smooth muscles throughout the body the leiomyosarcoma affects.Continue Reading
With leiomyosarcoma found in the gastrointestinal tract, patients experience abdominal pain, explains the National Organization for Rare Disorders. Symptoms include vomiting up blood or passing black, tarry, bad-smelling stool. Leiomyosarcoma in a woman's uterus produces abnormal bleeding or discharge. Most leiomyosarcomas originate in the retroperitoneum, states The Liddy Shriver Sarcoma Initiative. This area in the abdomen found behind the membrane is called the peritoneum.
Leiomyosarcomas are aggressive cancers, and the prognosis for one of these malignancies metastasizing is not good, according to the National Center for Biotechnology Information, U.S. National Library of Medicine. The overall 5-year survival rate for patients who had a liver resection, after a leiomyosarcoma had metastasized to the organ, is 13 percent. There were no 5-year survivors after a repeat liver resection.
Medical experts do not know specifically what causes leiomyosarcoma, explains the National Organization for Rare Disorders. Some experts believe it occurs when something goes wrong in the DNA of the patients. The abnormalities can be inherited or develop spontaneously.Learn more about Cancer