The symptoms of leiomyosarcoma include a mass in the abdomen, weight loss, nausea and vomiting, swelling and pain if it's found in the retroperitoneum, says the Liddy Shriver Sarcoma Initiative. If the leiomyosarcoma is found in the soft tissues, it presents as a mass that grows larger and larger, though it is painless. If it comes from a large blood vessel, it interferes with the vessel and causes edema in the limb.
In women, the symptoms of leiomyosarcomas include abnormal vaginal bleeding and pelvic pain or pain in the lower abdomen, according to Mount Sinai Hospital.
Treatments for leiomyosarcoma depends on where the cancer is found and its stage, according to Mount Sinai Hospital. One treatment is radiation therapy after most of the cancer and some local lymph nodes have been removed surgically. The radiation can be delivered externally or internally. During external radiation, a machine delivers radiation to the diseased area. If the radiation is internal, radioactive substances are inserted into the body near the cancer.
Chemotherapy uses drugs, either taken orally, by injection or intravenously to kill the malignancy, says Mount Sinai Hospital. However, chemotherapy is used for only certain kinds of leiomyosarcomas. It is sometimes used not to cure the disease but to slow it down and ease the patient's symptoms.