Symptoms of Ledderhose disease, also known as plantar fibroma, include a painful mass in the middle of the arch or instep of the bottom of the foot, explains the American Orthopaedic Foot and Ankle Society. The mass that develops with the condition causes a soft bump on the bottom of the foot that makes patients unable to wear shoes or put pressure on the foot without experiencing pain.
Ledderhose disease is a rare disorder that is more common in men than women, explains the Journal of Clinical and Aesthetic Dermatology. The condition is often associated with forms of fibromatosis.
Nodules and masses that form on the bottom of the foot in patients with Ledderhose disease are typically less than an inch in size, according to the American Orthopaedic Foot and Ankle Society. As of 2015, the cause of the condition is unknown. To diagnose Ledderhose disease, doctors typically perform a clinical exam and order an X-ray or MRI to inspect the mass or nodule. A biopsy of the foot is not usually necessary.
Treatment typically involves wearing shoe pads or off-loading insoles to relieve pain, states the American Orthopaedic Foot and Ankle Society. Patient activity is restricted, and the foot should be elevated to control swelling and prevent the formation of blood clots. Patients who do not respond to conservative treatment and develop symptomatic fibromas may require surgery.