The most common symptom of ionized calcium depression is neuromuscular irritibility, which includes muscle spasms, twitching and muscle cramping, according to the Cleveland Clinic and Chemocare. Additional symptoms may include increased or decreased heart rate, numbness and, in severe cases, coma, explains Healthline.
Calcium is essential for proper nerve and muscle function. The characteristic symptoms of ionized calcium depression are a result of impaired nerve and muscle function due to inadequate calcium levels in the bloodstream, says Chemocare.
The severity of symptoms varies depending on the degree to which calcium levels are below normal, according to the Cleveland Clinic. With mild to moderately depressed calcium levels, a person may show no symptoms or experience only a mild numbness and tingling in the fingers and toes, according to Chemocare. Depression and irritability are also common in mild cases. In more severe cases, confusion and disorientation may occur. Heart beat irregularities can also develop. If left untreated, severe cases of ionized calcium depression can result in coma.
Calcium levels can be measured through a simple blood test, explains Healthline. However, only a trained medical professional can assess symptoms and recommend treatment. Persons experiencing numbness, muscle spasms, twitching or any other unexplained symptoms should consult with a physician.