Symptoms of Buerger's disease include leg, foot, hand or arm pain that comes and goes; vein inflammation; pale fingers and toes in cold conditions; and open sores on the fingers and toes, according to Mayo Clinic. The pain often appears when using the hands or feet.
It is common for the pain from Buerger's disease to subside once patients stop engaging in an activity that requires them to use their hands or feet, explains Mayo Clinic. The vein inflammation experienced by Buerger's disease patients is the result of a blood clot in the affected vein and develops just underneath the surface of the skin. Most commonly, patients first develop symptoms in their hands and feet, and the symptoms may later spread to the arms or legs.
Buerger's disease is a medical condition involving blood clots, swelling and inflammation in the blood vessels, states Mayo Clinic. Over time, the condition results in destruction of skin tissue, potentially leading to gangrene or infections. Almost all Buerger's disease patients use tobacco products, such as cigarettes or chewing tobacco, and quitting these substances can stop the disease from progressing. Failure to stop using tobacco products can lead to limb amputation. Most individuals with the disease are men below the age of 40.