The most prominent symptom of a bot fly infection in humans is a hard, raised lesion on the skin's surface that may become painful, according to the University of Florida. A patient may also feel the fly larvae moving when taking a shower or covering the lesion.
Additionally, people who experience bot fly infections sometimes have elevated white blood cell counts, states the University of Florida. This sometimes causes the lesion to secrete pus.
Treatment of a bot fly infection in humans usually includes a simple surgery with local anesthesia to cut into the skin and carefully remove the larvae, states the University of Florida.