Some of the common symptoms that bone marrow cancers cause are bone pain, weakness or fatigue, weight loss, and fever. While these symptoms occur with multiple myeloma and leukemia, patients may experience other symptoms as well, according to Johns Hopkins Medicine.
Other symptoms that a patient with multiple myeloma may experience include broken bones, often in the spine; constipation; nausea; frequent urination; excessive thirst; and frequent infections. With leukemia, some patients have night sweats; a feeling of fullness under the left side of the ribs; painless lumps in the groin, neck or underarm; easy bleeding or bruising; and anemia, lists Johns Hopkins Medicine.
Multiple myeloma is a cancer that affects plasma cells, a type of white blood cell that creates antibodies to fight diseases and infections in the body. Cancerous plasma cells occur in the bone marrow and accumulate, overwhelming normal cells and invading bone tissue. This causes weakness and damage to the bones, explains Johns Hopkins Medicine.
Leukemia also starts in the bone marrow and causes the production of cancerous white blood cells. These cells do not die when they should, causing the healthy white and red blood cells and platelets to be become crowded out. With fewer normal blood cells, the body begins to experience the symptoms of leukemia, says Mayo Clinic.