Potential symptoms of plasma cell neoplasms include fatigue, bone pain, weakness and fevers, says the National Cancer Institute. Brittle, easily breakable bones are also present in some cases.
A plasma cell neoplasm is a disease that causes the human body to produce too many plasma cells, reports the National Cancer Institute. Cancerous in nature, malignant neoplasms can trigger cases of a dangerous disease called hypercalcemia. This serious illness is associated with appetite loss, confused thinking, nausea and constipation. Trouble breathing is also symptomatic of malignant, cancerous neplasms.
Plasma cell neoplasms can cause plasma cells to manufacture the M protein antibody, a fault that leads to abnormally thick blood, explains the NCI. These abnormal antibodies may harm kidneys as well. Most cancerous plasma cell neoplasms are classifed as plasmacytoma, or multiple myeloma. Multiple myeloma occurs when abnormally produced plasma cells build up within bones and create tumors throughout the body. In addition to damaging bones, multiple myeloma disrupts normal production of red blood cells.
Plasma cell neoplasms are more common in middle-aged people and senior citizens, with males more at risk than females, notes the NCI. Physicians typically use blood and urine tests to diagnose plasma cell neoplasms. In some cases, physicians might conduct bone marrow biopsies, which involve removing and analyzing small pieces of bone.