The five-year relative survival rate for leiomyosarcoma ranges from 14 percent to 68 percent depending on the staging of the disease, reports the American Cancer Society. A relative survival rate compares the rate of survival for the general population against the survival rate for those diagnosed with the disease.
Leiomyosarcoma is a form of sarcoma, a rare type of cancer that affects connective tissue, such as muscle, bone and cartilage, according to the LeioMyoSarcoma Direct Research Foundation. Leiomyosarcoma can appear in virtually any part of the body that hosts connective tissue, but it most often affects the uterus, notes WebMD. Doctors typically classify it as a form of uterine cancer. A diagnosis of stage 1, or localized, leiomyosarcoma means the cancer is restricted to the uterus and has the best prognosis, reports the American Cancer Society. A diagnosis of stage 2 or stage 3 leiomyosarcoma, also called regional leiomyosarcoma, means the cancer has spread to adjacent tissues, organs or lymph nodes. Stage 4, or distant, leiomyosarcoma occurs when the cancer metastasizes to areas of the body far from the original location of the cancer.
Late-stage leiomyosarcomas have a much lower survival rate than early-stage leiomyosarcomas. Stage 1 leiomyosarcoma has a 63 percent survival rate, stage 2 and stage 3 leiomyosarcomas have a 36 percent survival rate, and stage 4 leiomyosarcoma has a 14 percent survival rate. Treatment options vary according to the staging of the disease and include surgery, chemotherapy, radiation and hormone therapy, according to the American Cancer Society.