Sulfamethoxazole with trimethoprimis a combination of two drugs and is used to treat bacterial infections, such as pneumonia, bronchitis, travelers' diarrhea and infections involving the ears, urinary tract and intestines, according to MedlinePlus. Sulfamethoxazole, also referred to as co-trimoxazole, is classified as a sulfonamide antibiotic.
Patients with a history of severe allergies, asthma, low folic acid levels, thyroid problems or blood disorders should notify their physician before taking sulfamethoxazole with trimethoprim, according to MedlinePlus. Sulfamethoxazole with trimethoprim is not recommended for pregnant women, as it can harm an unborn baby. Because this medication sometimes causes skin to become sensitive to sunlight, patients are advised to avoid excessive sun exposure and wear sunscreen, sunglasses and protective attire while taking sulfamethoxazole with trimethoprim.
Side effects, such as nausea, vomiting and loss of appetite, sometimes occur while taking sulfamethoxazole with trimethoprim and should be reported if they are severe or persistent, states MedlinePlus. Immediate medical care is advised for patients who experience any serious side effects, including rash, itching, fever, chills and sore throat. Severe diarrhea, unusual bruising or bleeding, yellowing of the skin or eyes, cough and shortness of breath are other serious side effects that may occur while taking sulfamethoxazole with trimethoprim.