Stage IV kidney cancer is cancer of the kidney that has spread outside the confines of the organ to other areas of the body, according to the American Cancer Society. Treatment options at this stage are dependent on the patient's overall health and how much the cancer has spread.
Texas Oncology explains that local and systemic treatments are normally used to treat stage IV kidney cancer. Local treatment involves surgical removal of the affected kidney, attached adrenal gland and surrounding fat, lymph nodes and blood vessels. Systemic treatments include chemotherapy, immunotherapy and targeted therapy that seek to destroy cancer cells that have developed in other areas of the body. Chemotherapy utilizes drugs to eradicate cancer cells, immunotherapy stimulates the body's immune system to combat any remaining cancer, and targeted therapy targets destruction of cancer cells while having minimal effect on normal cells.