Prolotherapy injection solutions contain substances such as erythropoietin, a hormone used in growth factor injection prolotherapy; a simple 10 percent dextrose solution for growth factor stimulation prolotherapy; and 12.5 percent to 25 percent dextrose phenol-containing-solutions for inflammatory prolotherapy, states the American Association of Orthopaedic Medicine. Sodium-morrhuate-containing solutions are also used.
Prolotherapy is the injection of any anesthetic agents and natural substances that promote growth or stimulate healing of normal organs, tissues or cells. While glucose is often used in the injection solution, each physician selects the substances based on the patient's needs, notes the American Association of Orthopaedic Medicine. For example, a mildly irritating solution, precisely injected into a stretched or torn tendon or ligament, creates a mild, controlled injury that stimulates the body's natural healing processes. The body begins to form new tissue over the damaged or weak area.